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By: Driving substantial weight loss Improving blood sugar and insulin sensitivity Reducing inflammation Lowering LDL cholesterol it could become one of the most powerful tools in preventing heart diseasethe #1 cause of death worldwide

Lipids required for ATG8 lipidation and membrane extension are delivered to the phagophore via ATG2 and ATG9, where ATG9 acts as a seed to initiate lipid transfer by ATG2 that acts as a hose funneling lipids from relevant compartments (e.g., the ER) to the phagophore (5254, 7678) ( Figure 1 , panel 3)

PMC11499218 Hou, A., Cohen, B., Haimovic, A., & Elbuluk, N

Therefore, the two major effects that are enhanced by IGF-1 are FFA use by muscle and GH suppression